B.S., Lehigh University (1999)

           M.S., Lehigh University (2001)

           Ph.D., Lehigh University (2005)

           Postdoctoral Research, Texas A&M University,
           Department of Chemistry (2005-2007)

          


      Dr. Daniel received her undergraduate and graduate degrees from Lehigh University in the department of chemical engineering. She specialized in the area of surface science, studying the effect of surface wettability gradients on the motion of liquid droplets when they are subjected to coalescence or vibration. During these pioneering studies, she developed protocols for fluid management in miniaturized fluidic devices. Using her protocols, she then created miniaturized batch-wise processes on a chip as an alternative to continuous flow lab-on-a-chip paradigms. Within a small chip, she actuated and controlled drop motion and drop mixing on surfaces as well as carried out thermosensitive reactions inside such drops. During the final years of her graduate study with Professor Manoj Chaudhury, she showed how temporal asymmetry of a periodic signal in conjunction with interfacial hysteresis can be used to create ratcheting motion of drops on surfaces. During this phase of research she also collaborated with Professor P.G. de Gennes, which led to a joint publication in Langmuir that was subsequently featured in the Analytical Currents news section of Analytical Chemistry in June 2005. Her graduate work resulted in publications in Science, Langmuir, and the Proceedings of the National Academy of Sciences .

      In 2005, Dr. Daniel joined Professor Paul Cremer's group at Texas A&M University in the department of chemistry. There she expanded her expertise into the area of biological surface science. Specifically, Dr. Daniel used solid-supported lipid bilayers (SLBs) as mimics of the cell membrane to carry out novel investigations, with a common theme of separations of membrane species. Dr. Daniel worked on a team that devised an artificial glycocalyx-like structure on SLBs that was used as a nanoscale size-selective filter for protein binding experiments. This work allowed proteins to be screened from the bulk solution above the SLB, based on the protein size, so that binding specificity was enhanced. These studies then inspired Dr. Daniel to use an SLB as a separation medium itself, to separate membrane-bound species using electrophoresis within the plane of the SLB. Such work is a significant step forward in the goal of separating transmembrane species in their native environments to preserve their structure and function. Both of these topics were published in the Journal of the American Chemical Society and were featured in the Analytical Currents news section of Analytical Chemistry. In addition to the separation studies that Dr. Daniel conducted, she also worked on biosensor development and novel methods to determine diffusion coefficients in SLBs. Some of this work was also published in Journal of the American Chemical Society and Langmuir .

      Dr. Daniel's independent research career will focus on surface science, biological interfaces, and engineering of novel devices for applications ranging from material transport in microfludic devices to biological assays and sensors. Visit the Research link to the left to find out more about specific projects and the research mission of our group.


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