B.S., Chem. Eng., Lehigh University (1999)
M.S., Chem. Eng., Lehigh University (2001)
Ph.D., Chem. Eng., Lehigh University (2005)
Postdoctoral Research, Texas A&M University,
Department of Chemistry (2005-2007)
Visiting Scientist, Ecole Nationale Superieure
des Mines de Saint Etienne (2014-2015)
NSF CAREER AWARD, 2011
Denice Denton Emerging Leader Award, 2012
Zellman Warhaft Commitment to Diversity Award, 2014
Professor Daniel received her undergraduate and graduate degrees from Lehigh University in the department of
chemical engineering. She specialized in the area of surface science, studying the effect of surface wettability gradients on the
motion of liquid droplets when they are subjected to coalescence or vibration. During these pioneering studies, she developed protocols
for fluid management in miniaturized fluidic devices. Using her protocols, she then created miniaturized batch-wise processes on a chip
as an alternative to continuous flow lab-on-a-chip paradigms. Within a small chip, she actuated and controlled drop motion and drop mixing
on surfaces as well as carried out thermosensitive reactions inside such drops. During the final years of her graduate study with Professor Manoj
Chaudhury, she showed how temporal asymmetry of a periodic signal in conjunction with interfacial hysteresis can be used to create ratcheting
motion of drops on surfaces. During this phase of research she also collaborated with Noble Laureate, Professor P.G. de Gennes, which led to a joint
publication in Langmuir that was subsequently featured in the Analytical Currents news section of Analytical Chemistry in June 2005.
Her graduate work resulted in publications in Science, Langmuir, and the Proceedings of the National Academy
of Sciences .
In 2005, Prof. Daniel joined Professor Paul Cremer's group at Texas A&M University in the department of chemistry. There she expanded her expertise into the area of biological surface science. Specifically, Dr. Daniel used solid-supported lipid bilayers (SLBs) as mimics of the cell membrane to carry out novel investigations, with a common theme of separations of membrane species. Dr. Daniel worked on a team that devised an artificial glycocalyx-like structure on SLBs that was used as a nanoscale size-selective filter for protein binding experiments. This work allowed proteins to be screened from the bulk solution above the SLB, based on the protein size, so that binding specificity was enhanced. These studies then inspired Dr. Daniel to use an SLB as a separation medium itself, to separate membrane-bound species using electrophoresis within the plane of the SLB. Such work was a significant step forward in the goal of separating transmembrane species in their native environments to preserve their structure and function. Both of these topics were published in the Journal of the American Chemical Society and were featured in the Analytical Currents news section of Analytical Chemistry. In addition to the separation studies that Dr. Daniel conducted, she also worked on biosensor development and novel methods to determine diffusion coefficients in SLBs. Some of this work was also published in Journal of the American Chemical Society and Langmuir .
Prof. Daniel began her independent laboratory at Cornell in 2007. The common theme of the Daniel research group is investigating dynamic phenomena at biological interfaces and chemically patterned surfaces that interact with soft matter – liquids; polymers; and biological materials, like cells, viruses, proteins, and lipids. Her group has pioneered development of single particle tracking assays to study pathogen-host interactions, and the development of virus-like proteoliposomes and supported planar bilayers that facilitate those studies. Her groups also studies protein-lipid interactions and develops novel devices to study protein and glycolipid partitioning into lipid rafts along with the biological effects of this partitioning. Finally, her group has continued work on the interactions of liquid droplets with surface and the dynamics of those interactions during vibration and drop coalescence.
Prof. Daniel was promoted to Associate Professor with tenure in 2014. She is the recipient of a National Science Foundation CAREER award in 2011, the Denice Denton Emerging Leader Award in 2012, and the Zellman Warhaft Commitment to Diversity Award in 2014. She is also the faculty advisor for the Chemical and Biomolecular Engineering graduate women’s group (CBE Women), which serves to provide professional development and leadership opportunities to graduate students to complement their graduate education.
Prof. Daniel has taught sophomore-level Mass and Energy Balances; graduate level Physical and Chemical Kinetics, and the graduate seminar class; Principles and Practices of Graduate Research.