Surajit Ghosh

 

 

Postdoctoral Research Associate

Chemical and Biomolecular Engineering

sg2382@cornell.edu

LinkedIn

 

Awards

• National Fellowship from Council of Scientific and Industrial Research (CSIR), Govt. of India
• Awarded Merit-Cum-Means (MCM) Scholarship, IIT Kharagpur

 

Research

I am focused on the formation and characterization of supported lipid bilayers (SLB) using mammalian and bacterial cell membranes on conducting polymer surfaces. As part of my research, I isolate cell blebs from mammalian cells and outer membrane vesicles (OMVs) from bacteria and rupture them on conducting polymer-coated glass slides. Then I characterize the membranes using Fluorescence Recovery After Photobleaching (FRAP) and Quartz Microbalance with Dissipation (QCM-D). These SLB platforms can be used for a variety of studies including virus fusion, ion channel activity, and protein dynamics.

Publications

1. Ghosh, X. Wang, J. Wang, P.-D. Nguyen, C. M. Janczak, and C. A. Aspinwall. “Enhanced Fluorescent Protein Activity in Polymer Scaffold Stabilized Phospholipid Nanoshells using Neutral Redox Initiator Polymerization Conditions” ACS Omega, 2018, 3, 15890–15899.
2. Ghosh, A. Roy, D. Banik, N. Kundu, J. Kuchlyan, A. Dhir, and N. Sarkar, “How Does the Surface Charge of Ionic Surfactant and Cholesterol forming Vesicles Control Rotational Dynamics and Translational Diffusion of Rhodamine 6G Perchlorate (R6GClO₄)?” Langmuir, 2015, 31, 2310–2320.
3. Ghosh, D. Banik, A. Roy, N. Kundu, J. Kuchlyan, and N. Sarkar, “Spectroscopic investigation of the binding interactions of a membrane potential molecule in various supramolecular confined environments: contrasting behavior of surfactant molecules in relocation or release of the probe between nanocarriers and DNA surface” Phys. Chem. Chem. Phys., 2014, 16, 25024–25038.
4. Ghosh, J. Kuchlyan, S. Roychowdhury, D. Banik, N. Kundu, A. Roy, and N. Sarkar “Unique Influence of Cholesterol on Modifying the Aggregation Behavior of Surfactant Assemblies: Investigation of Photophysical and Dynamical Properties of 2,2′-Bipyridine-3,3′-diol, BP(OH)2 in Surfactant Micelles, and Surfactant/Cholesterol Forming Vesicles” J. Phys. Chem. B, 2014, 118, 9329–9340.
5. Ghosh, J. Kuchlyan, D. Banik, N. Kundu, A. Roy, C. Banerjee, and N. Sarkar, “Organic Additive, 5-Methylsalicylic Acid Induces Spontaneous Structural Transformation of Aqueous Pluronic Triblock Copolymer Solution: A Spectroscopic Investigation of Interaction of Curcumin with Pluronic Micellar and Vesicular Aggregates” J. Phys. Chem. B, 2014, 118, 11437–11448.
6. Ghosh, C. Ghatak, C. Banerjee, S. Mandal, J. Kuchlyan, and N. Sarkar, “Spontaneous Transition of Micelle–Vesicle–Micelle in a Mixture of Cationic Surfactant and Anionic Surfactant-like Ionic Liquid: A Pure Nonlipid Small Unilamellar Vesicular Template Used for Solvent and Rotational Relaxation Study” Langmuir, 2013, 29, 10066–10076.
7. Ghosh, C. Banerjee, S. Mandal, V. G. Rao, and N. Sarkar “Effect of Alkyl Chain of Room Temperature Ionic Liquid (RTILs) on the Phase Behavior of [C₂mim][C_nSO₄]/TX-100/Cyclohexane Microemulsions: Solvent and Rotational Relaxation Study” J. Phys. Chem. B, 2013, 117, 5886–5897.
8. Ghosh, S. Mandal, C. Banerjee, V. G. Rao, and N. Sarkar, “Photophysics of 3,3′-diethyloxadicarbocyanine iodide (DODCI) in Ionic Liquid Micelle and Binary Mixtures of Ionic Liquids: Effect of Confinement and Viscosity on Photoisomerization Rate” J. Phys. Chem. B, 2012, 116, 9482-9491.
9. Mandal, S. Ghosh, D. Banik, C. Banerjee, J. Kuchlyan, and N. Sarkar. “An Investigation into the Effect of the Structure of Bile Salt Aggregates on the Binding Interactions and ESIHT Dynamics of Curcumin: A Photophysical Approach to Probe Bile Salt Aggregates as a Potential Drug Carrier” J. Phys. Chem. B, 2013, 117, 13795–13807.
10. Mandal, S. Ghosh, C. Banerjee, J. Kuchlyan, and N. Sarkar. “Unique Photophysical Behavior of 2,2′-Bipyridine-3,3′-diol in DMSO–Water Binary Mixtures: Potential Application for Fluorescence Sensing of Zn²⁺ Based on the Inhibition of Excited-State Intramolecular Double Proton Transfer” J. Phys. Chem. B, 2013, 117, 12212–12223.

   

Fun Facts

When I’m not in the lab, I enjoy traveling. During my time in the US, I have visited twelve states: California, Arizona, Utah, Texas, New York, Pennsylvania, Florida, Illinois, Missouri, Maryland, Washington D.C., and Washington. I look forward to visiting all fifty states in order to learn about regional nuances because this knowledge helps me work with diverse teams. My hobbies outside of travel are cooking, hiking, and following my favorite teams: Barcelona Football, English Premier League, and Team India Cricket.