Postdoctoral Research Associate
Chemical and Biomolecular Engineering
- National Fellowship from Council of Scientific and Industrial Research (CSIR), Govt. of India
- Awarded Merit-Cum-Means (MCM) Scholarship, IIT Kharagpur
I am focused on the formation and characterization of supported lipid bilayers (SLB) using mammalian and bacterial cell membranes on conducting polymer surfaces. As part of my research, I isolate cell blebs from mammalian cells and outer membrane vesicles (OMVs) from bacteria and rupture them on conducting polymer-coated glass slides. Then I characterize the membranes using Fluorescence Recovery After Photobleaching (FRAP) and Quartz Microbalance with Dissipation (QCM-D). These SLB platforms can be used for a variety of studies including virus fusion, ion channel activity, and protein dynamics.
- Ghosh, X. Wang, J. Wang, P.-D. Nguyen, C. M. Janczak, and C. A. Aspinwall. “Enhanced Fluorescent Protein Activity in Polymer Scaffold Stabilized Phospholipid Nanoshells using Neutral Redox Initiator Polymerization Conditions” ACS Omega, 2018, 3, 15890–15899.
- Ghosh, A. Roy, D. Banik, N. Kundu, J. Kuchlyan, A. Dhir, and N. Sarkar, “How Does the Surface Charge of Ionic Surfactant and Cholesterol forming Vesicles Control Rotational Dynamics and Translational Diffusion of Rhodamine 6G Perchlorate (R6GClO4)?” Langmuir, 2015, 31, 2310–2320.
- Ghosh, D. Banik, A. Roy, N. Kundu, J. Kuchlyan, and N. Sarkar, “Spectroscopic investigation of the binding interactions of a membrane potential molecule in various supramolecular confined environments: contrasting behavior of surfactant molecules in relocation or release of the probe between nanocarriers and DNA surface” Phys. Chem. Chem. Phys., 2014, 16, 25024–25038.
- Ghosh, J. Kuchlyan, S. Roychowdhury, D. Banik, N. Kundu, A. Roy, and N. Sarkar “Unique Influence of Cholesterol on Modifying the Aggregation Behavior of Surfactant Assemblies: Investigation of Photophysical and Dynamical Properties of 2,2′-Bipyridine-3,3′-diol, BP(OH)2 in Surfactant Micelles, and Surfactant/Cholesterol Forming Vesicles” J. Phys. Chem. B, 2014, 118, 9329–9340.
- Ghosh, J. Kuchlyan, D. Banik, N. Kundu, A. Roy, C. Banerjee, and N. Sarkar, “Organic Additive, 5-Methylsalicylic Acid Induces Spontaneous Structural Transformation of Aqueous Pluronic Triblock Copolymer Solution: A Spectroscopic Investigation of Interaction of Curcumin with Pluronic Micellar and Vesicular Aggregates” J. Phys. Chem. B, 2014, 118, 11437–11448.
- Ghosh, C. Ghatak, C. Banerjee, S. Mandal, J. Kuchlyan, and N. Sarkar, “Spontaneous Transition of Micelle–Vesicle–Micelle in a Mixture of Cationic Surfactant and Anionic Surfactant-like Ionic Liquid: A Pure Nonlipid Small Unilamellar Vesicular Template Used for Solvent and Rotational Relaxation Study” Langmuir, 2013, 29, 10066–10076.
- Ghosh, C. Banerjee, S. Mandal, V. G. Rao, and N. Sarkar “Effect of Alkyl Chain of Room Temperature Ionic Liquid (RTILs) on the Phase Behavior of [C2mim][CnSO4]/TX-100/Cyclohexane Microemulsions: Solvent and Rotational Relaxation Study” J. Phys. Chem. B, 2013, 117, 5886–5897.
- Ghosh, S. Mandal, C. Banerjee, V. G. Rao, and N. Sarkar, “Photophysics of 3,3′-diethyloxadicarbocyanine iodide (DODCI) in Ionic Liquid Micelle and Binary Mixtures of Ionic Liquids: Effect of Confinement and Viscosity on Photoisomerization Rate” J. Phys. Chem. B, 2012, 116, 9482-9491.
- Mandal, S. Ghosh, D. Banik, C. Banerjee, J. Kuchlyan, and N. Sarkar. “An Investigation into the Effect of the Structure of Bile Salt Aggregates on the Binding Interactions and ESIHT Dynamics of Curcumin: A Photophysical Approach to Probe Bile Salt Aggregates as a Potential Drug Carrier” J. Phys. Chem. B, 2013, 117, 13795–13807.
- Mandal, S. Ghosh, C. Banerjee, J. Kuchlyan, and N. Sarkar. “Unique Photophysical Behavior of 2,2′-Bipyridine-3,3′-diol in DMSO–Water Binary Mixtures: Potential Application for Fluorescence Sensing of Zn2+ Based on the Inhibition of Excited-State Intramolecular Double Proton Transfer” J. Phys. Chem. B, 2013, 117, 12212–12223.